What We Do

The CINRG network is a collaborative group of more than 20 sites that performs clinical studies in neuromuscular disorders. The goals of the studies that we run vary, from monitoring and observing patients over time to gain an understanding of the natural course of progression of a particular disease, to testing the safety and efficacy of a promising new drug or a drug that is used in other disease states and may work in neuromuscular disorders, to comparing the efficacy of two drugs. To date CINRG has completed a total of 6 clinical studies and is currently running several others. While most of our focus has been on Duchenne and Becker Muscular Dystrophy, we are currently running a study in Limb-Girdle Muscular Dystrophy. We hope to continue with our current research in Becker and Duchenne Muscular Dystrophy and expand into other neuromuscular disorders.

The "Sponsor" of our clinical studies, or the entity that initiates and is responsible for the study, can be CINRG itself, a company or a non-profit organization that wants to use CINRG to run a trial or a government agency that wants to fund research. Sometimes it is the collaborative efforts of some of these groups that provide the leadership and funding for a study. Not every site participates in every study as it depends on the number of patients that is needed to fulfill the statistical requirements of a study, the interest level of the site in the study goal and the particular logistical requirements a study may have. There are many federal and international rules and regulations that govern the conduct of clinical studies and CINRG prides itself in maintaining standards that meet or exceed these requirements. The FDA has more information available at understanding clinical studies.